Repaglinide is a medication used to manage blood sugar levels in people with type 2 diabetes. It is an oral antidiabetic drug that helps lower blood glucose levels by stimulating the release of insulin from the pancreas. Below is a comprehensive overview of Repaglinide, including its medication description, uses, dosage, contraindications, warnings and precautions, side effects, storage, pharmacist tips, and frequently asked questions (FAQs):
MEDICATION DESCRIPTION
Repaglinide is available under the brand name Prandin. It is a white to off-white powder that is practically insoluble in water and soluble in methanol and ethanol. Repaglinide comes in tablet form, typically in 0.5 mg, 1 mg, and 2 mg strengths.
USES
- Repaglinide is used to treat type 2 diabetes in adults.
- It helps control blood sugar levels by increasing insulin release from the pancreas, especially during meals.
- It is often prescribed in combination with a proper diet and exercise program.
DOSAGE
- The usual starting dose for Repaglinide is 0.5 mg before each main meal (3 times a day) or as directed by a healthcare provider.
- The dose can be adjusted based on blood glucose levels and the individual’s response to the medication.
- The maximum recommended daily dose is 16 mg.
CONTRAINDICATIONS
- Do not take Repaglinide if you are allergic to it or have a history of allergic reactions to it.
- Repaglinide is not recommended for use in type 1 diabetes or diabetic ketoacidosis.
WARNINGS AND PRECAUTIONS
- Repaglinide may cause low blood sugar (hypoglycemia). Be cautious when driving or operating machinery, especially if you experience low blood sugar symptoms like dizziness or shakiness.
- Inform your healthcare provider of all the medications you are taking, as some drugs may interact with Repaglinide.
- It should be taken 15 to 30 minutes before meals.
- Check your blood sugar levels regularly as directed by your doctor.
- Do not change your dose or stop taking Repaglinide without consulting your healthcare provider.
SIDE EFFECTS
Common side effects may include:
- Hypoglycemia (low blood sugar)
- Headache
- Upper respiratory tract infection
- Back pain
Less common, but more severe side effects may include:
- Severe hypoglycemia leading to loss of consciousness
- Liver problems
Contact your healthcare provider if you experience any unusual or severe side effects.
STORAGE
- Store Repaglinide at room temperature (between 68°F to 77°F or 20°C to 25°C).
- Keep it away from light and moisture.
- Do not store in the bathroom.
- Keep it out of reach of children and pets.
PHARMACIST TIPS
- Take Repaglinide with meals to help control post-meal blood sugar spikes.
- Be consistent with your meal times to maintain a regular dosing schedule.
- Always carry a source of fast-acting sugar (like glucose tablets) to treat low blood sugar.
Repaglinide FAQs
Can I take Repaglinide if I have type 1 diabetes?
No, Repaglinide is specifically intended for people with type 2 diabetes and should not be used in type 1 diabetes.
How quickly does Repaglinide work to lower blood sugar?
Repaglinide works quickly and should be taken 15 to 30 minutes before a meal to help control blood sugar spikes after eating.
Can I drink alcohol while taking Repaglinide?
You should be cautious when consuming alcohol, as it can interact with Repaglinide and increase the risk of hypoglycemia. Consult your doctor for specific guidance.
What should I do if I miss a dose of Repaglinide?
If you miss a dose, take it as soon as you remember. However, if it’s time for your next dose, skip the missed dose and continue with your regular dosing schedule.
Is Repaglinide safe during pregnancy and breastfeeding?
Consult your healthcare provider if you are pregnant, planning to become pregnant, or breastfeeding, as the safety of Repaglinide in these situations is not well established.
Always consult your healthcare provider or pharmacist for personalized information and guidance regarding the use of Repaglinide, as individual circumstances may vary.
