MEDICATION DESCRIPTION
Janumet is a prescription medication that combines two active ingredients, sitagliptin and metformin. Sitagliptin belongs to a class of drugs called DPP-4 inhibitors, and metformin is a biguanide antidiabetic medication. This combination is used to treat type 2 diabetes in adults by helping to control blood sugar levels.
USES
Janumet is used to manage blood sugar levels in people with type 2 diabetes. It works by increasing the release of insulin and reducing the amount of sugar produced and released by the liver. It can be used alone or in combination with other medications or insulin as part of a comprehensive diabetes management plan.
DOSAGE
The dosage of Janumet will vary depending on the individual’s medical condition and response to treatment. It is typically taken with meals. Your healthcare provider will determine the appropriate dosage for you.
CONTRAINDICATIONS
- Do not use Janumet if you have type 1 diabetes.
- Do not use Janumet if you have a history of an allergic reaction to sitagliptin or metformin.
- Janumet should not be used in patients with severe kidney disease.
- It is not recommended for use during pregnancy or breastfeeding.
WARNINGS AND PRECAUTIONS
- Janumet should be used with caution in patients with kidney problems. Your doctor will determine the appropriate dose in such cases.
- It may cause a rare but serious condition called lactic acidosis, particularly in individuals with kidney or liver problems.
- It may increase the risk of pancreatitis.
- Inform your healthcare provider of all the medications and supplements you are taking to avoid potential drug interactions.
SIDE EFFECTS
Common side effects of Janumet may include:
- Stomach upset
- Diarrhea
- Nausea
- Headache
- Hypoglycemia (low blood sugar), especially when used with other antidiabetic medications
Serious side effects may include:
- Signs of lactic acidosis (e.g., muscle pain or weakness, trouble breathing, stomach pain, feeling cold)
- Signs of pancreatitis (e.g., severe stomach or back pain, nausea, vomiting)
- Allergic reactions (rash, itching, swelling, severe dizziness, difficulty breathing)
INTERACTIONS
Janumet may interact with other medications, including those that affect blood sugar levels. Some common drug interactions include:
- Insulin or sulfonylureas
- Certain diuretics
- Certain antihypertensive medications
- Corticosteroids
- Some antibiotics
Inform your healthcare provider about all the medications and supplements you are taking to avoid potentially harmful interactions.
STORAGE
Store Janumet at room temperature away from light and moisture. Keep it out of the reach of children.
PHARMACIST TIPS
- Take Janumet exactly as prescribed by your healthcare provider.
- Be consistent with your diet and exercise routine while taking Janumet.
- Be vigilant for signs of low blood sugar (hypoglycemia) while on Janumet, especially if taking other antidiabetic medications.
Janumet FAQs
What should I do if I miss a dose of Janumet?
Take the missed dose as soon as you remember. If it’s close to the time for your next dose, skip the missed dose and continue with your regular schedule.
Can I drink alcohol while taking Janumet?
Alcohol can affect blood sugar levels and should be consumed in moderation. Consult your healthcare provider for personalized advice.
Is Janumet safe during pregnancy?
It’s generally not recommended during pregnancy. Consult your doctor for alternative treatment options if you become pregnant or plan to become pregnant.
Can I crush or break Janumet tablets for easier swallowing?
No, it’s best to swallow the tablets whole.
How often should I have my kidney function monitored while on Janumet?
Your healthcare provider will determine the frequency of kidney function tests based on your individual needs and risk factors.
Remember that Janumet should only be used under the guidance and supervision of a healthcare professional. This information is for reference and should not replace professional medical advice.
