What Is Apixaban (Eliquis)?
Apixaban, sold under the brand name Eliquis, is a prescription anticoagulant (blood thinner) used to prevent blood clots. It belongs to a class of medications called direct oral anticoagulants (DOACs), which help reduce the risk of stroke and systemic embolism in people with atrial fibrillation (AFib) not caused by a heart valve problem.
Doctors also prescribe Apixaban to treat or prevent deep vein thrombosis (DVT) and pulmonary embolism (PE) — conditions where clots form in the legs or lungs.
How Does Apixaban Work?
Apixaban works by blocking Factor Xa, a key enzyme in the blood-clotting process. By slowing this step, it prevents clots from forming too easily while still allowing normal blood flow.
Unlike older anticoagulants like Warfarin, Apixaban doesn’t require frequent INR blood testing or major dietary restrictions, making it a convenient option for many patients.
Common Uses of Apixaban
Preventing stroke in patients with non-valvular atrial fibrillation
Treating DVT and PE
Preventing DVT after hip or knee replacement surgery
Reducing the risk of recurrent DVT or PE after treatment
Apixaban vs. Warfarin
| Feature | Apixaban (Eliquis) | Warfarin |
|---|---|---|
| Monitoring | No regular INR tests | Frequent INR tests required |
| Diet Restrictions | None | Avoid high-vitamin-K foods |
| Onset of Action | Rapid (within hours) | Slow (takes several days) |
| Drug Interactions | Fewer | Many |
Because of its convenience and reliability, Apixaban has become one of the most prescribed anticoagulants in the U.S..
Possible Side Effects
While Apixaban is generally well-tolerated, all blood thinners carry a risk of bleeding.
Common side effects may include:
Easy bruising or nosebleeds
Minor gum bleeding
Nausea
Seek medical attention immediately if you experience:
Heavy or uncontrolled bleeding
Red or dark urine / black stools
Sudden severe headache or dizziness
Important Safety Information
Never stop taking Apixaban without talking to your doctor — suddenly stopping can increase your risk of stroke.
Inform all healthcare providers, including dentists, that you’re taking Apixaban before any procedures.
Avoid combining Apixaban with certain pain relievers (like NSAIDs) or herbal supplements unless approved by your healthcare provider.
Apixaban (Eliquis) Cost Savings from Canada
Apixaban can be expensive in the U.S., with average retail prices often exceeding $500 per month.
By ordering through a licensed Canadian pharmacy, U.S. patients can access the same medication for up to 80% less — with genuine product sourced from regulated suppliers.
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